- Sacha Bennett (1 movie)
- Sam Fell (3 movies)
- Sam Irvin (1 movie)
- Sam Liu (2 movies)
- Sam Mendes (4 movies)
- Sam Raimi (6 movies)
- Sam Taylor-Johnson (1 movie)
- Sam Weisman (1 movie)
- Sandra Nettelbeck (1 movie)
- Sarah Smith (1 movie)
- Saul Dibb (1 movie)
- Scott Cooper (2 movies)
- Scott Derrickson (5 movies)
- Scott Foley (1 movie)
- Scott Frank (2 movies)
- Scott Hicks (2 movies)
- Scott Mann (2 movies)
- Scott Moore (1 movie)
- Scott Stewart (2 movies)
- Scott Walker (1 movie)
- Scott Waugh (2 movies)
- Scott Wiper (1 movie)
- Sean Anders (2 movies)
- Sean Ellis (1 movie)
- Sean Garrity (1 movie)
- Sean Penn (1 movie)
- Sebastián Cordero (1 movie)
- Sebastian Gutierrez (1 movie)
- Sergey Bodrov (2 movies)
- Seth Barrish (1 movie)
- Seth Gordon (3 movies)
- Seth Green (2 movies)
- Seth MacFarlane (2 movies)
- Seth Rogen (1 movie)
- Shamim Sarif (1 movie)
- Shane Abbess (1 movie)
- Shane Black (3 movies)
- Shane Meadows (1 movie)
- Shari Springer Berman (1 movie)
- Sharon Maguire (1 movie)
- Shawn Levy (6 movies)
- Sian Heder (1 movie)
- Sidney Lumet (1 movie)
- Simon Curtis (2 movies)
- Simon Hunter (1 movie)
- Simon J. Smith (2 movies)
- Simon West (4 movies)
- Sofia Coppola (1 movie)
- Soi Cheang (1 movie)
- Sophie Goodhart (1 movie)