- David Morrissey (4 movies)
- David Murray (4 movies)
- David Paymer (4 movies)
- David Rasche (4 movies)
- David Ryall (4 movies)
- David Schwimmer (4 movies)
- David Tennant (4 movies)
- David Wain (4 movies)
- David Wilmot (4 movies)
- David Zayas (4 movies)
- Dayo Okeniyi (4 movies)
- Debi Derryberry (4 movies)
- Deborah Kara Unger (4 movies)
- Demián Bichir (4 movies)
- Deneen Tyler (4 movies)
- Dermot Crowley (4 movies)
- Dev Patel (4 movies)
- Devon Aoki (4 movies)
- Dexter Fletcher (4 movies)
- Diedrich Bader (4 movies)
- Diego Luna (4 movies)
- Diora Baird (4 movies)
- Dominic Monaghan (4 movies)
- Don Thompson (4 movies)
- Donald Faison (4 movies)
- Donald Fullilove (4 movies)
- Donald Glover (4 movies)
- Dougray Scott (4 movies)
- Dustin Milligan (4 movies)
- Dallas Roberts (5 movies)
- Damion Poitier (5 movies)
- Damon Wayans Jr. (5 movies)
- Dane Cook (5 movies)
- Daniel Bacon (5 movies)
- Daniel Cudmore (5 movies)
- Daniel Sunjata (5 movies)
- Dave Bautista (5 movies)
- David Costabile (5 movies)
- David Denman (5 movies)
- David Duchovny (5 movies)
- Delroy Lindo (5 movies)
- Devon Murray (5 movies)
- Dianne Wiest (5 movies)
- Domenick Lombardozzi (5 movies)
- Donna DuPlantier (5 movies)
- Dorian Missick (5 movies)
- Doug Jones (5 movies)
- Douglas M. Griffin (5 movies)
- Dylan Baker (5 movies)
- Dylan Kenin (5 movies)