- Sylvester McCoy (3 movies)
- S. Scott Bullock (2 movies)
- Sachiko Fujii (2 movies)
- Saige Fernandes (2 movies)
- Sakalas Uždavinys (2 movies)
- Sakichi Satô (2 movies)
- Sal Mineo (2 movies)
- Sam Creed (2 movies)
- Sam Harris (2 movies)
- Sam J. Jones (2 movies)
- Sam Lerner (2 movies)
- Sam Medina (2 movies)
- Sam Raimi (2 movies)
- Sam Robards (2 movies)
- Sam Trammell (2 movies)
- Samantha Barks (2 movies)
- Samantha Morton (2 movies)
- Samantha Weinstein (2 movies)
- Samara Lee (2 movies)
- Samia Shoaib (2 movies)
- Sandra Nelson (2 movies)
- Santiago Segura (2 movies)
- Sara Forestier (2 movies)
- Sara Mornell (2 movies)
- Sara Paxton (2 movies)
- Sarah Burns (2 movies)
- Sarah Carter (2 movies)
- Sarah Chalke (2 movies)
- Sarah Douglas (2 movies)
- Sarah Flind (2 movies)
- Sarah G. Buxton (2 movies)
- Sarah Greene (2 movies)
- Sarah Lancaster (2 movies)
- Sarah McLeod (2 movies)
- Sarah Polley (2 movies)
- Sarah Ramos (2 movies)
- Sarah Smyth (2 movies)
- Sarah-Jane Redmond (2 movies)
- Sascha Knopf (2 movies)
- Sasha Roiz (2 movies)
- Sasha Spielberg (2 movies)
- Scott Dymond (2 movies)
- Scott Grimes (2 movies)
- Scott Heindl (2 movies)
- Scott Johnsen (2 movies)
- Scott MacDonald (2 movies)
- Scott McCord (2 movies)
- Scott Mechlowicz (2 movies)
- Scott Shepherd (2 movies)
- Scottie Thompson (2 movies)