- Simon Bird (2 movies)
- Simon Helberg (2 movies)
- Simon Kassianides (2 movies)
- Simon Russell Beale (2 movies)
- Simone Kessell (2 movies)
- Sinbad (2 movies)
- Sinéad Cusack (2 movies)
- Sinead Matthews (2 movies)
- Skandar Keynes (2 movies)
- Sô Yamanaka (2 movies)
- Sofia Boutella (2 movies)
- Song Kang-ho (2 movies)
- Sonny Chiba (2 movies)
- Sophia Myles (2 movies)
- Sophia Takal (2 movies)
- Sophie Curtis (2 movies)
- Sophie Marceau (2 movies)
- Sophie Stuckey (2 movies)
- Sophie Wu (2 movies)
- Sophie-Anna Brough (2 movies)
- Soren Fulton (2 movies)
- Spencer Drever (2 movies)
- Spencer Lofranco (2 movies)
- Spencer Treat Clark (2 movies)
- Stacy Edwards (2 movies)
- Stana Katic (2 movies)
- Stanislav Ianevski (2 movies)
- Stanley B. Herman (2 movies)
- Steele Gagnon (2 movies)
- Stef Dawson (2 movies)
- Stefan Kalipha (2 movies)
- Stefanie von Pfetten (2 movies)
- Stella Schnabel (2 movies)
- Steph Song (2 movies)
- Stephanie Kurtzuba (2 movies)
- Stephanie Mace (2 movies)
- Stephanie March (2 movies)
- Stephanie Sigman (2 movies)
- Stephen Amell (2 movies)
- Stephen Billington (2 movies)
- Stephen Caudill (2 movies)
- Stephen Collins (2 movies)
- Stephen Dunham (2 movies)
- Stephen Greif (2 movies)
- Stephen Hunter (2 movies)
- Stephen Huszar (2 movies)
- Stephen J. Anderson (2 movies)
- Stephen Moyer (2 movies)
- Stephen Rannazzisi (2 movies)
- Stephen Spinella (2 movies)