- Owen Finnegan (1 movie)
- Owen Clarke (1 movie)
- Owen Burke (2 movies)
- Owen Best (1 movie)
- Owain Yeoman (1 movie)
- Ousaun Elam (1 movie)
- Otto Sanchez (1 movie)
- Osric Chau (2 movies)
- Osmani Rodriguez (2 movies)
- Osi Okerafor (1 movie)
- Oshri Cohen (1 movie)
- Oscar Torre (1 movie)
- Oscar Pearce (1 movie)
- Oscar Nunez (2 movies)
- Oscar Kightley (1 movie)
- Óscar Jaenada (3 movies)
- Oscar Isaac (11 movies)
- Oscar Hatton (1 movie)
- Oscar Gale (1 movie)
- Óscar Casas (1 movie)
- Oscar Beard (1 movie)
- Orto Ignatiussen (1 movie)
- Orso Maria Guerrini (1 movie)
- Orlando Wells (1 movie)
- Orlando Jones (2 movies)
- Orlando Brown (1 movie)
- Orlando Bloom (12 movies)
- Orla O'Rourke (1 movie)
- Orla Hill (1 movie)
- Orion John (1 movie)
- Orianthi (1 movie)
- Oreste Baldini (1 movie)
- Orbert Rogers (1 movie)
- Orangey (1 movie)
- Oran Gurel (1 movie)
- Oprah Winfrey (3 movies)
- Ophelia Lovibond (2 movies)
- Opal Alladin (1 movie)
- Oona Laurence (1 movie)
- Oona Chaplin (2 movies)
- Onni Tommila (1 movie)
- Onira Tares (1 movie)
- Ong Soo Han (1 movie)
- Onalee Ames (1 movie)
- Ona Grauer (2 movies)
- Omiros Poulakis (1 movie)
- Omid Djalili (4 movies)
- Omid Abtahi (3 movies)
- Omero Capanna (1 movie)
- Omari Hardwick (2 movies)